BZIP28
Gene Ontology Biological Process
- endoplasmic reticulum unfolded protein response [IGI]
- positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [IMP]
- regulation of transcription, DNA-templated [ISS]
- response to endoplasmic reticulum stress [IEP]
- response to heat [IEP, IMP]
- response to unfolded protein [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NF-YC2
Gene Ontology Biological Process
Gene Ontology Molecular Function
PCA
A Protein-Fragment Complementation Assay (PCA) is a protein-protein interaction assay in which a bait protein is expressed as fusion to one of the either N- or C- terminal peptide fragments of a reporter protein and prey protein is expressed as fusion to the complementary N- or C- terminal fragment of the same reporter protein. Interaction of bait and prey proteins bring together complementary fragments, which can then fold into an active reporter, e.g. the split-ubiquitin assay.
Publication
bZIP28 and NF-Y transcription factors are activated by ER stress and assemble into a transcriptional complex to regulate stress response genes in Arabidopsis.
Stress agents known to elicit the unfolded protein response in Arabidopsis thaliana upregulate the expression of a constellation of genes dependent on the membrane-associated basic domain/leucine zipper (bZIP) transcription factor, bZIP28. Among the stress-activated genes, a consensus promoter sequence corresponding to the endoplasmic reticulum (ER) stress-responsive element I (ERSE-I), CCAAT-N10-CACG, was identified. Disruption of either the CCAAT or CACG subelement ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID