BAIT

BAG7

ATBAG7, BCL-2-associated athanogene 7, MMI9.22, MMI9_22, AT5G62390
BCL-2-associated athanogene 7
GO Process (4)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

BIP2

BIP, MJC20.12, MJC20_12, luminal binding protein, AT5G42020
Luminal-binding protein 2
Arabidopsis thaliana (Columbia)

PCA

A Protein-Fragment Complementation Assay (PCA) is a protein-protein interaction assay in which a bait protein is expressed as fusion to one of the either N- or C- terminal peptide fragments of a reporter protein and prey protein is expressed as fusion to the complementary N- or C- terminal fragment of the same reporter protein. Interaction of bait and prey proteins bring together complementary fragments, which can then fold into an active reporter, e.g. the split-ubiquitin assay.

Publication

AtBAG7, an Arabidopsis Bcl-2-associated athanogene, resides in the endoplasmic reticulum and is involved in the unfolded protein response.

Williams B, Kabbage M, Britt R, Dickman MB

The Bcl-2-associated athanogene (BAG) family is an evolutionarily conserved, multifunctional group of cochaperones that perform diverse cellular functions ranging from proliferation to growth arrest and cell death in yeast, in mammals, and, as recently observed, in plants. The Arabidopsis genome contains seven homologs of the BAG family, including four with domain organization similar to animal BAGs. In the present study ... [more]

Proc. Natl. Acad. Sci. U.S.A. Mar. 30, 2010; 107(13);6088-93 [Pubmed: 20231441]

Throughput

  • Low Throughput

Curated By

  • BioGRID