BAIT

BANF1

BAF, BCRP1, D14S1460, NGPS

barrier to autointegration factor 1

GO Process (6)

GO Function (1)

GO Component (5)

Gene Ontology Biological Process

establishment of integrated proviral latency [TAS]

mitotic cell cycle [TAS]

mitotic nuclear envelope disassembly [TAS]

mitotic nuclear envelope reassembly [TAS]

response to virus [TAS]

viral process [TAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

extracellular vesicular exosome [IDA]

nucleoplasm [IDA, TAS]

CRISPR Database OMIM HGNC Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

SMARCC2

BAF170, CRACC2, Rsc8

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Autism spectrum disorder (ASD) Project

GO Process (6)

GO Function (5)

GO Component (7)

Gene Ontology Biological Process

ATP-dependent chromatin remodeling [IDA]

chromatin remodeling [IDA]

negative regulation of transcription, DNA-templated [IDA]

nucleosome disassembly [IDA]

positive regulation of transcription, DNA-templated [IDA]

regulation of transcription from RNA polymerase II promoter [NAS]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
nucleosomal DNA binding [IDA]
protein binding [IPI]
transcription coactivator activity [NAS]

Gene Ontology Cellular Component

SWI/SNF complex [IDA]

nBAF complex [ISS]

npBAF complex [ISS]

nuclear chromatin [IDA]

nucleoplasm [IDA]

protein complex [IDA]

transcriptional repressor complex [IPI]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.

Montes de Oca R, Shoemaker CJ, Gucek M, Cole RN, Wilson KL

Nuclear lamin filaments and associated proteins form a nucleoskeletal ("lamina") network required for transcription, replication, chromatin organization and epigenetic regulation in metazoans. Lamina defects cause human disease ("laminopathies") and are linked to aging. Barrier-to-autointegration factor (BAF) is a mobile and essential component of the nuclear lamina that binds directly to histones, lamins and LEM-domain proteins, including the inner nuclear membrane ... [more]

PLoS ONE Sep. 18, 2009; 4(9);e7050 [Pubmed: 19759913]

Throughput

Low Throughput

Curated By

BioGRID