BAIT
ADNP
ADNP1, MRD28
activity-dependent neuroprotector homeobox
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
SMARCC2
BAF170, CRACC2, Rsc8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
GO Process (6)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex.
Complete deficiency in activity-dependent neuroprotective protein (ADNP), a heterochromatin 1-binding protein, results in dramatic changes in gene expression, neural tube closure defects, and death at gestation day 9 in mice. To further understand the cellular roles played by ADNP, the HEK293 human embryonic kidney cell line that allows efficient transfection with recombinant DNA was used as a model for the ... [more]
J. Biol. Chem. Nov. 23, 2007; 282(47);34448-56 [Pubmed: 17878164]
Throughput
- Low Throughput
Curated By
- BioGRID