BAIT

BAK1

ATBAK1, ATSERK3, BRI1-associated receptor kinase, ELG, ELONGATED, F17M5.190, F17M5_190, RECEPTOR KINASES LIKE SERK 10, RKS10, SERK3, SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE 3, AT4G33430
Leu-rich receptor Serine/threonine protein kinase BAK1
Arabidopsis thaliana (Columbia)
PREY

PUB12

AtPUB12, F8N16.12, F8N16_12, PLANT U-BOX 12, AT2G28830
U-box E3 ubiquitin ligase
GO Process (2)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)

Biochemical Activity (Phosphorylation)

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

Direct ubiquitination of pattern recognition receptor FLS2 attenuates plant innate immunity.

Lu D, Lin W, Gao X, Wu S, Cheng C, Avila J, Heese A, Devarenne TP, He P, Shan L

Innate immune responses are triggered by the activation of pattern-recognition receptors (PRRs). The Arabidopsis PRR FLAGELLIN-SENSING 2 (FLS2) senses bacterial flagellin and initiates immune signaling through association with BAK1. The molecular mechanisms underlying the attenuation of FLS2 activation are largely unknown. We report that flagellin induces recruitment of two closely related U-box E3 ubiquitin ligases, PUB12 and PUB13, to FLS2 ... [more]

Science Jun. 17, 2011; 332(6036);1439-42 [Pubmed: 21680842]

Throughput

  • Low Throughput

Curated By

  • BioGRID