BAIT

TPR1

T21F11.18, T21F11_18, TOPLESS-related 1, AT1G80490
Topless-related protein 1
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

TMAC2

ABI FIVE BINDING PROTEIN 4, AFP4, F1C9.7, TWO OR MORE ABRES-CONTAINING GENE 2, AT3G02140
Ninja-family protein AFP4
GO Process (4)
GO Function (0)
GO Component (1)
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The TOPLESS Interactome: A Framework for Gene Repression in Arabidopsis.

Causier B, Ashworth M, Guo W, Davies B

Transcription factors activate or repress target gene expression, or switch between activation and repression. In animals and yeast, Groucho/Tup1 co-repressor proteins are recruited by diverse transcription factors to induce context-specific transcriptional repression. Two groups of Gro/Tup1-like co-repressors have been described in plants. LEUNIG (LUG) and LEUNIG_HOMOLOG (LUH) constitute one group and TOPLESS (TPL) and the four TPL-related (TPR) co-repressors form ... [more]

Unknown Nov. 07, 2011; 0(0); [Pubmed: 22065421]

Throughput

  • Low Throughput

Curated By

  • BioGRID