BAIT
HMOX2
HO-2
heme oxygenase (decycling) 2
GO Process (6)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BLOC1S2
BLOS2, CEAP, CEAP11, RP11-316M21.4
biogenesis of lysosomal organelles complex-1, subunit 2
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISS]
- anterograde synaptic vesicle transport [ISS]
- extrinsic apoptotic signaling pathway via death domain receptors [IDA]
- melanosome organization [NAS]
- microtubule nucleation [NAS]
- mitochondrial outer membrane permeabilization [IDA]
- neuron projection development [ISS]
- platelet dense granule organization [NAS]
- positive regulation of cell proliferation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IBA]
- positive regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID