BAIT
KCNA5
ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
potassium voltage-gated channel, shaker-related subfamily, member 5
GO Process (10)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- atrial cardiac muscle cell action potential [IMP]
- membrane hyperpolarization [IMP]
- potassium ion export [IDA, IMP]
- potassium ion transport [IDA]
- regulation of atrial cardiac muscle cell membrane repolarization [IMP]
- regulation of heart rate by cardiac conduction [IMP]
- regulation of insulin secretion [TAS]
- regulation of membrane potential [IDA]
- regulation of potassium ion transport [IMP]
- synaptic transmission [TAS]
Gene Ontology Molecular Function- alpha-actinin binding [IPI]
- delayed rectifier potassium channel activity [IDA, IMP]
- outward rectifier potassium channel activity [IDA, IMP]
- protein binding [IPI]
- protein kinase binding [IPI]
- scaffold protein binding [IPI]
- voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [IMP]
- alpha-actinin binding [IPI]
- delayed rectifier potassium channel activity [IDA, IMP]
- outward rectifier potassium channel activity [IDA, IMP]
- protein binding [IPI]
- protein kinase binding [IPI]
- scaffold protein binding [IPI]
- voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [IMP]
Gene Ontology Cellular Component
Homo sapiens
PREY
TFRC
CD71, T9, TFR, TFR1, TR, TRFR, p90
transferrin receptor
GO Process (6)
GO Function (5)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- blood microparticle [IDA]
- cell surface [IDA]
- coated pit [IDA]
- cytoplasmic membrane-bounded vesicle [IDA]
- endosome [IDA]
- extracellular region [IDA]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- integral component of plasma membrane [TAS]
- intracellular membrane-bounded organelle [IDA]
- membrane [NAS]
- plasma membrane [TAS]
- recycling endosome [IDA]
- vesicle [IDA]
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Kv1.5 association modifies Kv1.3 traffic and membrane localization.
Kv1.3 activity is determined by raft association. In addition to Kv1.3, leukocytes also express Kv1.5, and both channels control physiological responses. Because the oligomeric composition may modify the channel targeting to the membrane, we investigated heterotetrameric Kv1.3/Kv1.5 channel traffic and targeting in HEK cells. Kv1.3 and Kv1.5 generate multiple heterotetramers with differential surface expression according to the subunit composition. FRET ... [more]
J. Biol. Chem. Mar. 28, 2008; 283(13);8756-64 [Pubmed: 18218624]
Throughput
- Low Throughput
Curated By
- BioGRID