BAIT
MAGEC1
CT7, CT7.1, RP6-232G24.1
melanoma antigen family C, 1
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
ROCK2
ROCK-II
Rho-associated, coiled-coil containing protein kinase 2
GO Process (14)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- axon guidance [TAS]
- centrosome duplication [IMP]
- cytokinesis [NAS]
- negative regulation of angiogenesis [IMP]
- protein phosphorylation [IDA]
- regulation of actin cytoskeleton organization [TAS]
- regulation of cell adhesion [TAS]
- regulation of cell motility [TAS]
- regulation of circadian rhythm [ISS]
- regulation of establishment of cell polarity [TAS]
- regulation of focal adhesion assembly [TAS]
- regulation of keratinocyte differentiation [IMP]
- regulation of stress fiber assembly [TAS]
- smooth muscle contraction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6).
Cancer/testis (CT) antigens are the protein products of germ line-associated genes that are activated in a wide variety of tumors and can elicit autologous cellular and humoral immune responses. CT antigens can be divided between those that are encoded on the X chromosome (CT-X antigens) and those that are not (non-X CT antigens). Among the CT-X antigens, the melanoma antigen ... [more]
Cancer Immun. Dec. 02, 2006; 6(0);12 [Pubmed: 17137291]
Throughput
- Low Throughput
Curated By
- BioGRID