BAIT
TFRC
CD71, T9, TFR, TFR1, TR, TRFR, p90
transferrin receptor
GO Process (6)
GO Function (5)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- blood microparticle [IDA]
- cell surface [IDA]
- coated pit [IDA]
- cytoplasmic membrane-bounded vesicle [IDA]
- endosome [IDA]
- extracellular region [IDA]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- integral component of plasma membrane [TAS]
- intracellular membrane-bounded organelle [IDA]
- membrane [NAS]
- plasma membrane [TAS]
- recycling endosome [IDA]
- vesicle [IDA]
Homo sapiens
PREY
B4GALT1
B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
GO Process (14)
GO Function (9)
GO Component (12)
Gene Ontology Biological Process
- Notch signaling pathway [TAS]
- binding of sperm to zona pellucida [TAS]
- carbohydrate metabolic process [TAS]
- cellular protein metabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- keratan sulfate biosynthetic process [TAS]
- keratan sulfate metabolic process [TAS]
- multicellular organism reproduction [TAS]
- oligosaccharide biosynthetic process [IDA, NAS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation [IDA]
- protein N-linked glycosylation via asparagine [TAS]
- single fertilization [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- N-acetyllactosamine synthase activity [IDA]
- UDP-galactosyltransferase activity [IDA]
- alpha-tubulin binding [IDA]
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [IDA]
- beta-tubulin binding [IPI]
- galactosyltransferase activity [NAS]
- lactose synthase activity [IDA]
- manganese ion binding [IDA]
- protein homodimerization activity [IDA]
- N-acetyllactosamine synthase activity [IDA]
- UDP-galactosyltransferase activity [IDA]
- alpha-tubulin binding [IDA]
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [IDA]
- beta-tubulin binding [IPI]
- galactosyltransferase activity [NAS]
- lactose synthase activity [IDA]
- manganese ion binding [IDA]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins.
Recent studies on proteins residing in the Golgi complex revealed that the membrane-spanning domain of these proteins are largely responsible for their retention in the Golgi complex. We show here that beta-1,4-galactosyltransferase (GT) forms homodimers and large oligomers in vivo, and the formation of the homodimers is dependent on cysteine and histidine residues within the transmembrane domain. Double mutations of ... [more]
J. Biol. Chem. May. 19, 1995; 270(20);12170-6 [Pubmed: 7744867]
Throughput
- Low Throughput
Curated By
- BioGRID