BAIT

AT4G35910

T19K4.40
cytoplasmic tRNA 2-thiolation protein 2
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

ROL5

F4I1.8, repressor of lrx1, AT2G44270
ROL5, repressor of LRX1
GO Process (2)
GO Function (0)
GO Component (1)
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The cytosolic thiouridylase CTU2 of Arabidopsis thaliana is essential for posttranscriptional thiolation of tRNAs and influences root development.

Philipp M, John F, Ringli C

A large number of post-transcriptional modifications of transfer RNAs (tRNAs) have been described in prokaryotes and eukaryotes. They are known to influence their stability, turnover, and chemical/physical properties. A specific subset of tRNAs contains a thiolated uridine residue at the wobble position to improve the codon-anticodon interaction and translational accuracy. The proteins involved in tRNA thiolation are reminiscent of prokaryotic ... [more]

BMC Plant Biol. Apr. 30, 2014; 14(1);109 [Pubmed: 24774365]

Throughput

  • Low Throughput

Curated By

  • BioGRID