BioGRID Funding And Partners

BioGRID Partner National Institutes of Health NIH BioGRID Partner Canadian Inststitutes of Health Research BioGRID Partner Genome Quebec BioGRID Partner Mount Sinai Hospital BioGRID Partner Princeton University BioGRID Partner Universite de Montreal BioGRID Partner Saccharomyces Genome Database BioGRID Partner University of Edinburgh BioGRID Partner IMEX

Areas of Interest to Help You Get Started

Build and Download Interaction Datasets

Create custom interaction datasets by protein or by publication. You can also download our entire dataset in a wide variety of standard formats.

Link To Us or Submit Interactions

Send us your datasets or link to the BioGRID directly from your own website or database. Full details on how to contribute are available here.

Online Tools and Resources

We've developed tools that make use of BioGRID data. Check out the list of tools to see if we can help you work with our data.

View Our Interaction Statistics

Find out how many organisms, proteins, publications, and interactions are available in the current release of the BioGRID.

Latest Updates

Latest News

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 58,777 publications. These additions bring our total number of non-redundant interactions to 1,112,963, raw interactions to 1,423,105, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: May 1, 2017 - 4:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 58,514 publications. These additions bring our total number of non-redundant interactions to 1,111,552, raw interactions to 1,421,025, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: April 1, 2017 - 2:55 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 58,254 publications. These additions bring our total number of non-redundant interactions to 1,110,310, raw interactions to 1,418,871, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: March 1, 2017 - 4:21 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 58,006 publications. These additions bring our total number of non-redundant interactions to 1,108,169, raw interactions to 1,415,388, non-redundant chemical associations to 11,805, raw chemical associations to 27,745, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: February 1, 2017 - 2:18 am

Newly released BioGRID update paper for 2017 highlights many new and expanded features of the BioGRID website. The full publication is available online now:

The BioGRID interaction database: 2017 update
Andrew Chatr-aryamontri, Rose Oughtred, Lorrie Boucher, Jennifer Rust, Christie Chang, Nadine K. Kolas, Lara O'Donnell, Sara Oster, Chandra Theesfeld, Adnane Sellam, Chris Stark, Bobby-Joe Breitkreutz, Kara Dolinski and Mike Tyers
Nucleic Acids Res. (2016)

[Nucleic Acids Research][PubMed]

Posted: January 6, 2017 - 6:03 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 57,864 publications. These additions bring our total number of non-redundant interactions to 1,105,799, raw interactions to 1,412,140, non-redundant chemical associations to 11,805, raw chemical associations to 27,745, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: January 1, 2017 - 3:48 am

The BioGRID has loaded a new comprehensive SGA dataset of 326,790 high confidence genetic interactions in the budding yeast Saccharomyces cerevisae as reported by Costanzo et al in the publication: "A global genetic interaction network maps a wiring diagram of cellular function." (Science 2016) [Science][BioGRID][Pubmed]. The dataset and associated quantitative scores are available immediately online via all standard BioGRID searches and supported download formats.

A special thanks to the contributors Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, Lin ZY, Kuzmin E, Nelson J, Piotrowski JS, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat CF, Li SC, Li Z, Usaj MM, Okada H, Pascoe N, San Luis BJ, Sharifpoor S, Shuteriqi E, Simpkins SW, Snider J, Suresh HG, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya OG, Stagljar I, Xia T, Ohya Y, Gingras AC, Raught B, Boutros M, Steinmetz LM, Moore CL, Rosebrock AP, Caudy AA, Myers CL, Andrews B and Boone C.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

Posted: December 7, 2016 - 6:03 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 57,763 publications. These additions bring our total number of non-redundant interactions to 1,104,640, raw interactions to 1,410,457, non-redundant chemical associations to 11,805, raw chemical associations to 27,745, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: December 7, 2016 - 5:48 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 57,513 publications. These additions bring our total number of non-redundant interactions to 842,529, raw interactions to 1,079,789, non-redundant chemical associations to 11,805, raw chemical associations to 27,745, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: November 1, 2016 - 4:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 57,184 publications. These additions bring our total number of non-redundant interactions to 836,880, raw interactions to 1,073,218, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: October 1, 2016 - 3:22 am