small molecule

Loratadine

Synonyms/Brands: l, Claritin, Loratadina, Loratadinum, family dollar allergy relief

Loratadine is a derivative of azatadine and a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (histamine H1 antagonists) it lacks central nervous system depressing effects such as drowsiness.

Molecular Formula: C₂₂H₂₃ClN₂O₂

Molecular Weight:: 382.883

CAS:: 79794-75-5

ATC:: R06AX13

InChiKey:: JCCNYMKQOSZNPW-UHFFFAOYSA-N

InChi:: InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3

SMILES:: CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2

IUPAC Name:: ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0,]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate

DrugBank BindingDB ChEMBL PubChem ChemSpider KEGG Drug

Download Curated Data for this Chemical

447

Interactors 2
Chemical Interactions 11
Network

Chemical Summary

Loratadine