BAIT

MET17

MET15, MET25, bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17, L000001091, L000001088, YLR303W
O-acetyl homoserine-O-acetyl serine sulfhydrylase; required for Methionine and cysteine biosynthesis
GO Process (2)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)
PREY

YCT1

YLL055W
High-affinity cysteine-specific transporter; has similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene
GO Process (1)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Phenotypic Enhancement

A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Yct1p, a novel, high-affinity, cysteine-specific transporter from the yeast Saccharomyces cerevisiae.

Kaur J, Bachhawat AK

Cysteine transport in the yeast Saccharomyces cerevisiae is mediated by at least eight different permeases, none of which are specific for cysteine. We describe a novel, high-affinity, (K(m) = 55 microM), cysteine-specific transporter encoded by the ORF YLL055w that was initially identified by a combined strategy of data mining, bioinformatics, and genetic analysis. Null mutants of YLL055w, but not of ... [more]

Genetics Jun. 01, 2007; 176(2);877-90 [Pubmed: 17435223]

Throughput

  • Low Throughput

Ontology Terms

  • nutrient utilization (APO:0000096)

Curated By

  • BioGRID