BAIT
CDC25B
RP5-1009E24.3
cell division cycle 25B
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- centrosome [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- nucleoplasm [IDA, TAS]
- spindle pole [IDA]
Homo sapiens
PREY
MSH6
GTBP, GTMBP, HNPCC5, HSAP, p160
mutS homolog 6
GO Process (15)
GO Function (16)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IBA, IDA]
- DNA repair [IDA]
- determination of adult lifespan [ISS]
- intrinsic apoptotic signaling pathway [ISS]
- intrinsic apoptotic signaling pathway in response to DNA damage [IBA, ISS]
- isotype switching [IBA, ISS]
- maintenance of DNA repeat elements [IMP]
- meiotic mismatch repair [IBA, ISS]
- mismatch repair [IDA, IGI, IMP]
- negative regulation of DNA recombination [IDA]
- positive regulation of helicase activity [IDA]
- reciprocal meiotic recombination [IBA]
- response to UV [IBA, ISS]
- somatic hypermutation of immunoglobulin genes [IBA, ISS]
- somatic recombination of immunoglobulin gene segments [ISS]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID