Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies.
Plants are foundational for global ecological and economic systems, but most plant proteins remain uncharacterized. Protein interaction networks often suggest protein functions and open new avenues to characterize genes and proteins. We therefore systematically determined protein complexes from 13 plant species of scientific and agricultural importance, greatly expanding the known repertoire of stable protein complexes in plants. By using co-fractionation ... [more]
Cell Mar. 16, 2020; (); [Pubmed: 32191846]
Quantitative Score
- 0.640972944 [CF-MS score]
Throughput
- High Throughput
Additional Notes
- Co-fractionation MS (CF-MS) was carried out to identify high confidence protein interactions having an interaction score above a 10% FDR threshold (CF-MS score >= 0.509).
- Interactor A: Orthogroup ENOG411DWD0, Annotation: 26s proteasome regulatory subunit
- Interactor B: Orthogroup ENOG411DY9V, Annotation: One of the primary rRNA binding proteins it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit (By similarity)
Curated By
- BioGRID