BAIT
PAX8
paired box 8
GO Process (33)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- branching involved in ureteric bud morphogenesis [IEP]
- cellular response to gonadotropin stimulus [IDA]
- central nervous system development [IEP]
- inner ear morphogenesis [ISS]
- kidney development [IEP]
- mesenchymal to epithelial transition involved in metanephros morphogenesis [IEP]
- mesonephros development [ISS]
- metanephric S-shaped body morphogenesis [IEP]
- metanephric comma-shaped body morphogenesis [IEP]
- metanephric distal convoluted tubule development [ISS]
- metanephric epithelium development [IEP]
- metanephric nephron tubule formation [ISS]
- negative regulation of apoptotic process involved in metanephric collecting duct development [ISS]
- negative regulation of apoptotic process involved in metanephric nephron tubule development [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephros development [ISS]
- otic vesicle development [IEP]
- positive regulation of branching involved in ureteric bud morphogenesis [ISS]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- positive regulation of metanephric DCT cell differentiation [ISS]
- positive regulation of thyroid hormone generation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- pronephric field specification [ISS]
- pronephros development [ISS]
- regulation of apoptotic process [ISS]
- regulation of metanephric nephron tubule epithelial cell differentiation [ISS]
- regulation of thyroid-stimulating hormone secretion [IMP]
- thyroid gland development [IEP, IMP]
- thyroid-stimulating hormone signaling pathway [TAS]
- transcription, DNA-templated [IDA]
- urogenital system development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA, ISS]
- nucleus [IDA]
Homo sapiens
PREY
NIPBL
CDLS, CDLS1, IDN3, IDN3-B, Scc2
Nipped-B homolog (Drosophila)
GO Process (28)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- brain development [IMP]
- cellular protein localization [IMP]
- cellular response to DNA damage stimulus [IMP]
- cellular response to X-ray [IMP]
- cognition [IMP]
- developmental growth [IMP]
- ear morphogenesis [IMP]
- embryonic digestive tract morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- external genitalia morphogenesis [IMP]
- eye morphogenesis [IMP]
- face morphogenesis [IMP]
- forelimb morphogenesis [IMP]
- gall bladder development [IMP]
- heart morphogenesis [IMP]
- maintenance of mitotic sister chromatid cohesion [IMP]
- metanephros development [NAS]
- mitotic cell cycle [TAS]
- mitotic sister chromatid cohesion [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- outflow tract morphogenesis [IMP]
- positive regulation of histone deacetylation [IDA]
- regulation of developmental growth [IMP]
- regulation of embryonic development [IMP]
- regulation of hair cycle [IMP]
- sensory perception of sound [IMP]
- uterus morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID