BAIT
SBA
AAF56201, CG13598, DMTF125, Dm Sba, Dmel\CG13598, F125, TF125, Dmel_CG13598
six-banded
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
CG5854
Dmel\CG5854, anon-WO0118547.306, Dmel_CG5854
CG5854 gene product from transcript CG5854-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.
BRCA1-associated protein 1 (BAP1) is an ubiquitin carboxy-terminal hydrolase, which forms a multi-protein complex with different epigenetic factors, such as ASXL1-3 and FOXK1/2. At the chromatin level, BAP1 catalyzes the removal of mono-ubiquitination on histone H2AK119 in collaboration with other subunits within the complex and functions as a transcriptional activator in mammalian cells. However, the crosstalk between different subunits and ... [more]
Genome Biol Sep. 30, 2022; 23(1);206 [Pubmed: 36180891]
Throughput
- Low Throughput
Curated By
- BioGRID