BAIT
CG1105
Dmel\CG1105, Dmel_CG1105
CG1105 gene product from transcript CG1105-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
TOR
5092, CG5092, CT16317, CT24745, CT24817, DmTOR, Dmel\CG5092, FRAP/TOR, dTOR, l(2)k17004, mTOR, Dmel_CG5092
Target of rapamycin
GO Process (25)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
- axon guidance [IGI]
- cellular response to DNA damage stimulus [IMP]
- dendrite morphogenesis [IMP]
- detection of nutrient [TAS]
- determination of adult lifespan [IMP]
- endocytic recycling [IDA]
- gonad development [IMP]
- growth [TAS]
- multicellular organism growth [IMP]
- myoblast fusion [IMP]
- negative regulation of macroautophagy [IMP]
- phosphorylation [NAS]
- phototaxis [IGI]
- positive regulation of cell growth [NAS, TAS]
- positive regulation of cell size [IGI, IMP, TAS]
- positive regulation of multicellular organism growth [TAS]
- positive regulation of organ growth [TAS]
- positive regulation of protein phosphorylation [IGI]
- positive regulation of ribosome biogenesis [IMP]
- regulation of cell growth [IDA]
- regulation of reactive oxygen species metabolic process [IGI]
- regulation of response to drug [IMP]
- response to nutrient [TAS]
- somatic muscle development [IMP]
- synaptic growth at neuromuscular junction [IGI]
Gene Ontology Molecular Function
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Comparative interactome analysis of ?-arrestin families in human and Drosophila.
The ?-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike ?-arrestins, only a few ?-arrestin targets and functions have been characterized. Here, using affinity purification and mass spectrometry, we constructed interactomes for 6 human and 12 Drosophila ?-arrestins. The resulting high-confidence interactomes comprised ... [more]
Elife Jan. 25, 2024; 12(); [Pubmed: 38270169]
Throughput
- High Throughput
Additional Notes
- Affinity capture MS was carried out to identify high confident protein interactors with a FDR of less than or equal to 0.01 and a minimum spectral count of 6
Curated By
- BioGRID