BAIT
ARRDC3
TLIMP
arrestin domain containing 3
GO Process (1)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A17
PMP34, RP3-362J20.2
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
GO Process (12)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
- ADP transport [IDA]
- AMP transport [IDA]
- ATP transport [IGI]
- FAD transmembrane transport [IDA]
- NAD transport [IDA]
- cellular lipid metabolic process [TAS]
- coenzyme A transmembrane transport [IDA]
- fatty acid alpha-oxidation [TAS]
- fatty acid beta-oxidation [IGI]
- fatty acid transport [IGI]
- nucleotide transmembrane transport [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- ADP transmembrane transporter activity [IDA]
- AMP transmembrane transporter activity [IDA]
- ATP transmembrane transporter activity [IGI]
- FAD transmembrane transporter activity [IDA]
- FMN transmembrane transporter activity [IDA]
- NAD transporter activity [IDA]
- chaperone binding [IPI]
- coenzyme A transmembrane transporter activity [IDA]
- protein binding [IPI]
- ADP transmembrane transporter activity [IDA]
- AMP transmembrane transporter activity [IDA]
- ATP transmembrane transporter activity [IGI]
- FAD transmembrane transporter activity [IDA]
- FMN transmembrane transporter activity [IDA]
- NAD transporter activity [IDA]
- chaperone binding [IPI]
- coenzyme A transmembrane transporter activity [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Comparative interactome analysis of ?-arrestin families in human and Drosophila.
The ?-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike ?-arrestins, only a few ?-arrestin targets and functions have been characterized. Here, using affinity purification and mass spectrometry, we constructed interactomes for 6 human and 12 Drosophila ?-arrestins. The resulting high-confidence interactomes comprised ... [more]
Elife Jan. 25, 2024; 12(); [Pubmed: 38270169]
Throughput
- High Throughput
Additional Notes
- Affinity capture MS was carried out to identify high confident protein interactors with a FDR of less than or equal to 0.01 and a minimum spectral count of 6
Curated By
- BioGRID