BAIT
CEBPB
Il6dbp, NF-IL6, TCF5
CCAAT/enhancer binding protein (C/EBP), beta
GO Process (18)
GO Function (11)
GO Component (6)
Gene Ontology Biological Process
- brown fat cell differentiation [ISO]
- cellular response to amino acid stimulus [ISO]
- embryonic placenta development [ISO]
- fat cell differentiation [ISO]
- mammary gland epithelial cell differentiation [ISO]
- mammary gland epithelial cell proliferation [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- neuron differentiation [ISO]
- positive regulation of fat cell differentiation [ISO, ISS]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of interleukin-6 biosynthetic process [ISO]
- regulation of transcription involved in cell fate commitment [ISO, ISS]
- regulation of transcription, DNA-templated [IC, ISO, ISS]
- response to endoplasmic reticulum stress [ISO, ISS]
- response to lipopolysaccharide [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO, ISS]
- chromatin binding [ISO]
- glucocorticoid receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- sequence-specific DNA binding [IDA, ISO]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
PREY
TPI1
HEL-S-49, TIM, TPI, TPID
triosephosphate isomerase 1
GO Process (5)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBP?.
CCAAT enhancer-binding protein beta (C/EBP?) is a pioneer transcription factor that specifies cell differentiation. C/EBP? is intrinsically unstructured, a molecular feature common to many proteins involved in signal processing and epigenetics. The structure of C/EBP? differs depending on alternative translation initiation and multiple post-translational modifications (PTM). Mutation of distinct PTM sites in C/EBP? alters protein interactions and cell differentiation, suggesting ... [more]
iScience Mar. 29, 2019; 13();351-370 [Pubmed: 30884312]
Throughput
- High Throughput
Additional Notes
- C/EBP beta core interactions
- PRISMA: Protein Interaction Screen on Peptide Matrix
Curated By
- BioGRID