BAIT

E6

HpV5gp1
transforming protein
GO Process (0)
GO Function (0)
GO Component (0)
Human papillomavirus (5)
PREY

TPI1

HEL-S-49, TIM, TPI, TPID
triosephosphate isomerase 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.

Howie HL, Koop JI, Weese J, Robinson K, Wipf G, Kim L, Galloway DA

The E6 oncoprotein from high-risk genus alpha human papillomaviruses (α-HPVs), such as HPV 16, has been well characterized with respect to the host-cell proteins it interacts with and corresponding signaling pathways that are disrupted due to these interactions. Less is known regarding the interacting partners of E6 from the genus beta papillomaviruses (β-HPVs); however, it is generally thought that β-HPV ... [more]

PLoS Pathog. Aug. 01, 2011; 7(8);e1002211 [Pubmed: 21901101]

Throughput

  • High Throughput

Ontology Terms

  • prepuce (BTO:0001113)
  • foreskin keratinocyte (CL:1001606)

Additional Notes

  • HFK

Curated By

  • BioGRID