BAIT

CHAC2

ChaC, cation transport regulator homolog 2 (E. coli)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

TPI1

HEL-S-49, TIM, TPI, TPID
triosephosphate isomerase 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

E3 ubiquitin ligase RNF148 functions as an oncogene in colorectal cancer by ubiquitination-mediated degradation of CHAC2.

Liu S, Zhuo L, Chen L, He Y, Chen X, Zhang H, Zhou Y, Ni Z, Zhao S, Hu X

We previously reported that RNF148 was involved in the ubiquitination-mediated degradation of CHAC2. However, its molecular mechanism was not determined. In this study, we investigated the role and mechanism of RNF148 in the progression of colorectal cancer (CRC), especially in the process of ubiquitination-mediated degradation of CHAC2. Our results revealed that RNF148 was upregulated in most CRC tissues, and its ... [more]

Carcinogenesis Apr. 12, 2024; 45(4);247-261 [Pubmed: 38190483]

Throughput

  • High Throughput

Curated By

  • BioGRID