Homo sapiens
CAPN3
CANP3, CANPL3, LGMD2, LGMD2A, nCL-1, p94
calpain 3, (p94)
GO Process (25)
GO Function (12)
GO Component (9)
Gene Ontology Biological Process
- apoptotic process [TAS]
- cellular response to calcium ion [ISS]
- cellular response to salt stress [ISS]
- muscle cell cellular homeostasis [TAS]
- muscle organ development [TAS]
- muscle structure development [ISS]
- myofibril assembly [ISS, TAS]
- negative regulation of apoptotic process [IMP]
- negative regulation of protein sumoylation [IDA]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of proteolysis [ISS]
- positive regulation of release of sequestered calcium ion into cytosol [ISS]
- positive regulation of satellite cell activation involved in skeletal muscle regeneration [ISS]
- positive regulation of transcription, DNA-templated [IMP]
- protein complex assembly [ISS]
- protein localization to membrane [ISS]
- proteolysis [IDA]
- regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- regulation of catalytic activity [IDA]
- response to calcium ion [ISS]
- response to muscle activity [ISS]
- sarcomere organization [ISS]
- self proteolysis [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function- calcium ion binding [ISS]
- calcium-dependent cysteine-type endopeptidase activity [IBA, ISS, TAS]
- catalytic activity [IDA]
- cysteine-type peptidase activity [TAS]
- ligase regulator activity [IDA]
- peptidase activity [IDA]
- protein binding [IPI]
- protein complex scaffold [ISS]
- signal transducer activity [TAS]
- sodium ion binding [ISS]
- structural constituent of muscle [ISS]
- titin binding [IPI]
- calcium ion binding [ISS]
- calcium-dependent cysteine-type endopeptidase activity [IBA, ISS, TAS]
- catalytic activity [IDA]
- cysteine-type peptidase activity [TAS]
- ligase regulator activity [IDA]
- peptidase activity [IDA]
- protein binding [IPI]
- protein complex scaffold [ISS]
- signal transducer activity [TAS]
- sodium ion binding [ISS]
- structural constituent of muscle [ISS]
- titin binding [IPI]
Download Curated Data for this Protein
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- Interactors 48
- Interactions 51
- Network