Homo sapiens
F2R
CF2R, HTR, PAR-1, PAR1, TR
coagulation factor II (thrombin) receptor
GO Process (45)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISS]
- STAT protein import into nucleus [IDA]
- activation of MAPKK activity [ISS]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- anatomical structure morphogenesis [TAS]
- blood coagulation [TAS]
- connective tissue replacement involved in inflammatory response wound healing [IDA]
- establishment of synaptic specificity at neuromuscular junction [ISS]
- homeostasis of number of cells within a tissue [ISS]
- inflammatory response [ISS]
- negative regulation of cell proliferation [IDA]
- negative regulation of glomerular filtration [ISS]
- negative regulation of neuron apoptotic process [ISS]
- negative regulation of renin secretion into blood stream [ISS]
- phospholipase C-activating G-protein coupled receptor signaling pathway [IDA]
- platelet activation [IDA, TAS]
- platelet dense granule organization [IC]
- positive regulation of ERK1 and ERK2 cascade [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IEP]
- positive regulation of JAK-STAT cascade [IDA]
- positive regulation of MAPK cascade [IDA]
- positive regulation of Rho protein signal transduction [ISS]
- positive regulation of blood coagulation [IDA]
- positive regulation of calcium ion transport [ISS]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [ISS]
- positive regulation of collagen biosynthetic process [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of cytosolic calcium ion concentration [ISS]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [ISS]
- positive regulation of interleukin-6 secretion [IDA]
- positive regulation of interleukin-8 secretion [IDA]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISS]
- positive regulation of release of sequestered calcium ion into cytosol [IDA]
- positive regulation of smooth muscle contraction [ISS]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of vasoconstriction [ISS]
- protein kinase C-activating G-protein coupled receptor signaling pathway [ISS]
- regulation of blood coagulation [IDA]
- regulation of interleukin-1 beta production [ISS]
- regulation of sensory perception of pain [ISS]
- release of sequestered calcium ion into cytosol [ISS]
- response to lipopolysaccharide [ISS]
- response to wounding [IDA]
- tyrosine phosphorylation of STAT protein [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
108448
9606
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- Interactors 36
- Interactions 46
- Chemical Interactions 2
- Network
- PTM Sites 8