Homo sapiens
HLA-DRB4
DR-4, DR4, DRB4, HLA-DR4B, DAMC-146E17.2
major histocompatibility complex, class II, DR beta 4
GO Process (20)
GO Function (3)
GO Component (13)
Gene Ontology Biological Process
- T cell costimulation [TAS]
- T cell receptor signaling pathway [TAS]
- T-helper 1 type immune response [ISS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- cytokine-mediated signaling pathway [TAS]
- detection of bacterium [ISS]
- humoral immune response mediated by circulating immunoglobulin [ISS]
- immune response [ISS]
- immunoglobulin production involved in immunoglobulin mediated immune response [ISS]
- inflammatory response to antigenic stimulus [IDA]
- interferon-gamma-mediated signaling pathway [TAS]
- negative regulation of T cell proliferation [ISS]
- negative regulation of inflammatory response to antigenic stimulus [IDA]
- negative regulation of interferon-gamma production [ISS]
- peptide antigen assembly with MHC class II protein complex [IDA]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [ISS]
- protein tetramerization [ISS]
- regulation of interleukin-10 secretion [ISS]
- regulation of interleukin-4 production [ISS]
- signal transduction [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- ER to Golgi transport vesicle membrane [TAS]
- Golgi membrane [TAS]
- MHC class II protein complex [IDA]
- clathrin-coated endocytic vesicle membrane [TAS]
- endocytic vesicle membrane [TAS]
- external side of plasma membrane [ISS]
- integral component of lumenal side of endoplasmic reticulum membrane [TAS]
- integral component of plasma membrane [TAS]
- late endosome membrane [IDA]
- lysosomal membrane [IDA, TAS]
- plasma membrane [TAS]
- trans-Golgi network membrane [TAS]
- transport vesicle membrane [TAS]
Download Curated Data for this Protein
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- Interactors 10
- Interactions 10
- Network
- PTM Sites 5