Homo sapiens
IL12B
CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
interleukin 12B
GO Process (46)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- T-helper 1 type immune response [TAS]
- T-helper cell differentiation [IDA]
- cell cycle arrest [IDA]
- cell migration [IDA]
- defense response to Gram-negative bacterium [IDA]
- interferon-gamma biosynthetic process [TAS]
- natural killer cell activation [IDA]
- negative regulation of interleukin-10 production [IMP]
- negative regulation of interleukin-17 production [IDA]
- negative regulation of smooth muscle cell proliferation [IDA]
- positive regulation of NF-kappaB import into nucleus [TAS]
- positive regulation of NK T cell activation [IC, IDA]
- positive regulation of NK T cell proliferation [IDA]
- positive regulation of T cell mediated cytotoxicity [ISS]
- positive regulation of T cell proliferation [IDA]
- positive regulation of T-helper 1 type immune response [IDA, ISS]
- positive regulation of T-helper 17 cell lineage commitment [ISS]
- positive regulation of T-helper 17 type immune response [ISS]
- positive regulation of activated T cell proliferation [IDA]
- positive regulation of activation of JAK2 kinase activity [IDA]
- positive regulation of cell adhesion [IDA]
- positive regulation of defense response to virus by host [IDA, ISS]
- positive regulation of granulocyte macrophage colony-stimulating factor production [IDA]
- positive regulation of inflammatory response [IC]
- positive regulation of interferon-gamma biosynthetic process [TAS]
- positive regulation of interferon-gamma production [IDA]
- positive regulation of interleukin-10 production [IDA, TAS]
- positive regulation of interleukin-12 production [IDA]
- positive regulation of interleukin-17 production [IDA]
- positive regulation of lymphocyte proliferation [IDA]
- positive regulation of memory T cell differentiation [ISS]
- positive regulation of mononuclear cell proliferation [IMP]
- positive regulation of natural killer cell activation [IC, IDA]
- positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [IDA]
- positive regulation of natural killer cell proliferation [IDA]
- positive regulation of osteoclast differentiation [IDA]
- positive regulation of smooth muscle cell apoptotic process [IDA]
- positive regulation of tissue remodeling [IC]
- positive regulation of tumor necrosis factor production [IMP]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IDA]
- positive regulation of tyrosine phosphorylation of Stat4 protein [IDA]
- positive regulation of tyrosine phosphorylation of Stat5 protein [IDA]
- regulation of cytokine biosynthetic process [TAS]
- regulation of tyrosine phosphorylation of Stat1 protein [IDA]
- response to UV-B [IDA]
- sexual reproduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
109807
9606
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- Interactors 5
- Interactions 6
- Chemical Interactions 8
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