Homo sapiens

MAP3K11

MEKK11, MLK-3, MLK3, PTK1, SPRK

mitogen-activated protein kinase kinase kinase 11

GO Process (9)

GO Function (7)

GO Component (3)

Gene Ontology Biological Process

JNK cascade [TAS]

activation of JUN kinase activity [IMP]

activation of MAPK activity [IMP]

cell proliferation [IMP]

microtubule-based process [IMP]

positive regulation of JNK cascade [IMP]

positive regulation of JUN kinase activity [IMP]

protein autophosphorylation [IDA]

protein phosphorylation [IDA]

Gene Ontology Molecular Function

JUN kinase kinase kinase activity [ISS]
identical protein binding [IPI]
mitogen-activated protein kinase kinase kinase binding [IPI]
protein binding [IPI]
protein homodimerization activity [IPI]
protein kinase activity [TAS]
protein serine/threonine kinase activity [IDA]

Gene Ontology Cellular Component

centrosome [IDA]

microtubule [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

110442

9606

Interactors 68
Interactions 88
Chemical Interactions 8
Network
PTM Sites 3