Homo sapiens
NKX3-1
BAPX2, NKX3, NKX3.1, NKX3A
NK3 homeobox 1
GO Process (40)
GO Function (14)
GO Component (2)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- androgen receptor signaling pathway [IDA]
- branching involved in prostate gland morphogenesis [ISS]
- branching morphogenesis of an epithelial tube [ISS]
- cellular response to drug [IEP]
- cellular response to hypoxia [IDA]
- cellular response to interleukin-1 [IEP]
- cellular response to steroid hormone stimulus [IDA]
- cellular response to tumor necrosis factor [IEP]
- epithelial cell proliferation involved in salivary gland morphogenesis [ISS]
- mitotic cell cycle arrest [IDA]
- multicellular organismal development [TAS]
- negative regulation of cell proliferation [IDA]
- negative regulation of epithelial cell proliferation [ISS]
- negative regulation of epithelial cell proliferation involved in prostate gland development [ISS]
- negative regulation of estrogen receptor binding [IDA]
- negative regulation of gene expression [IDA]
- negative regulation of insulin-like growth factor receptor signaling pathway [ISS]
- negative regulation of mitotic cell cycle [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of androgen secretion [IDA]
- positive regulation of apoptotic signaling pathway [IDA]
- positive regulation of cell death [IDA]
- positive regulation of cell division [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of gene expression [IDA, IMP]
- positive regulation of intrinsic apoptotic signaling pathway [IDA]
- positive regulation of mitotic cell cycle [IMP]
- positive regulation of phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of protein kinase activity [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of response to DNA damage stimulus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IMP, ISS]
- protein kinase B signaling [IMP]
- regulation of transcription, DNA-templated [NAS]
- response to testosterone [ISS]
- salivary gland development [ISS]
- steroid hormone mediated signaling pathway [IDA]
Gene Ontology Molecular Function- androgen receptor activity [IDA]
- core promoter binding [IDA]
- cysteine-type endopeptidase activator activity involved in apoptotic process [IDA]
- estrogen receptor activity [IDA]
- estrogen receptor binding [IDA]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein kinase activator activity [IDA]
- protein self-association [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- androgen receptor activity [IDA]
- core promoter binding [IDA]
- cysteine-type endopeptidase activator activity involved in apoptotic process [IDA]
- estrogen receptor activity [IDA]
- estrogen receptor binding [IDA]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein kinase activator activity [IDA]
- protein self-association [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
Download Curated Data for this Protein
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- Interactors 48
- Interactions 66
- Network
- PTM Sites 4