Homo sapiens

NPC1

NPC

Niemann-Pick disease, type C1

GO Process (10)

GO Function (5)

GO Component (10)

Gene Ontology Biological Process

autophagy [IGI]

bile acid metabolic process [ISS]

cholesterol efflux [IDA]

cholesterol homeostasis [IDA, ISS]

cholesterol transport [IDA]

establishment of protein localization to membrane [IDA]

lysosomal transport [ISS]

membrane raft organization [IMP]

protein glycosylation [IDA]

signal transduction [TAS]

Gene Ontology Molecular Function

cholesterol binding [IDA]
protein binding [IPI]
receptor activity [TAS]
sterol transporter activity [TAS]
transmembrane signaling receptor activity [TAS]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

extracellular region [ISS]

extracellular vesicular exosome [IDA]

integral component of membrane [TAS]

integral component of plasma membrane [IDA]

lysosomal membrane [IDA]

nuclear envelope [IDA]

perinuclear region of cytoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Download Curated Data for this Protein

110925

9606

Interactors 420
Interactions 464
Network
PTM Sites 54