BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Homo sapiens

NPC1

NPC

Niemann-Pick disease, type C1

GO Process (10)

GO Function (5)

GO Component (10)

Gene Ontology Biological Process

autophagy [IGI]

bile acid metabolic process [ISS]

cholesterol efflux [IDA]

cholesterol homeostasis [IDA, ISS]

cholesterol transport [IDA]

establishment of protein localization to membrane [IDA]

lysosomal transport [ISS]

membrane raft organization [IMP]

protein glycosylation [IDA]

signal transduction [TAS]

Gene Ontology Molecular Function

cholesterol binding [IDA]
protein binding [IPI]
receptor activity [TAS]
sterol transporter activity [TAS]
transmembrane signaling receptor activity [TAS]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

extracellular region [ISS]

extracellular vesicular exosome [IDA]

integral component of membrane [TAS]

integral component of plasma membrane [IDA]

lysosomal membrane [IDA]

nuclear envelope [IDA]

perinuclear region of cytoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

110925

9606

Interactors 397
Interactions 431
Network
PTM Sites 54