Homo sapiens
P2RX7
P2X7
purinergic receptor P2X, ligand-gated ion channel, 7
GO Process (21)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- apoptotic signaling pathway [ISS]
- bleb assembly [IDA, ISS]
- cation transmembrane transport [IDA]
- cation transport [IDA]
- cell surface receptor signaling pathway [ISS]
- innate immune response [TAS]
- membrane depolarization [IDA]
- negative regulation of MAPK cascade [ISS]
- negative regulation of bone resorption [ISS]
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]
- pore complex assembly [IDA]
- positive regulation of bone mineralization [ISS]
- positive regulation of calcium ion transport into cytosol [IDA]
- positive regulation of cytolysis [ISS]
- positive regulation of cytoskeleton organization [ISS]
- positive regulation of interleukin-1 beta secretion [IDA]
- purinergic nucleotide receptor signaling pathway [IDA]
- regulation of killing of cells of other organism [NAS]
- regulation of sodium ion transport [ISS]
- response to ATP [IDA]
- sensory perception of pain [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
111066
9606
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- Interactors 17
- Interactions 19
- Network