Homo sapiens
PF4
CXCL4, PF-4, SCYB4
platelet factor 4
GO Process (24)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IBA]
- blood coagulation [TAS]
- chemokine-mediated signaling pathway [IBA]
- cytokine-mediated signaling pathway [IDA]
- immune response [IBA]
- inflammatory response [IBA]
- leukocyte chemotaxis [IDA]
- negative regulation of MHC class II biosynthetic process [IDA]
- negative regulation of angiogenesis [IDA]
- negative regulation of cytolysis [IDA]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [IDA]
- negative regulation of megakaryocyte differentiation [IDA]
- platelet activation [IDA, TAS]
- platelet degranulation [TAS]
- positive regulation of cAMP metabolic process [IDA]
- positive regulation of cAMP-mediated signaling [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of leukocyte chemotaxis [IBA]
- positive regulation of macrophage derived foam cell differentiation [IDA]
- positive regulation of macrophage differentiation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of tumor necrosis factor production [IDA]
- regulation of cell proliferation [IDA]
- response to lipopolysaccharide [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
111219
9606
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- Interactors 30
- Interactions 42
- Chemical Interactions 1
- Network