Homo sapiens

PFN2

D3S1319E, PFL

profilin 2

GO Process (8)

GO Function (4)

GO Component (1)

Gene Ontology Biological Process

negative regulation of actin filament polymerization [IDA]

negative regulation of epithelial cell migration [IMP]

negative regulation of ruffle assembly [IMP]

positive regulation of ATPase activity [IDA]

positive regulation of actin filament bundle assembly [IMP]

positive regulation of actin filament polymerization [IGI]

positive regulation of peptidyl-serine phosphorylation [IMP]

positive regulation of stress fiber assembly [IMP]

Gene Ontology Molecular Function

actin monomer binding [IPI]
adenyl-nucleotide exchange factor activity [IDA]
phosphatidylinositol-4,5-bisphosphate binding [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

extracellular vesicular exosome [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

111238

9606

Interactors 151
Interactions 181
Chemical Interactions 2
Network
PTM Sites 12