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Homo sapiens

SERPINA1

A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, PRO0684

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

GO Process (5)

GO Function (5)

GO Component (6)

Gene Ontology Biological Process

blood coagulation [TAS]

negative regulation of endopeptidase activity [IBA]

platelet activation [TAS]

platelet degranulation [TAS]

regulation of proteolysis [IBA]

Gene Ontology Molecular Function

glycoprotein binding [IPI]
identical protein binding [IPI]
protease binding [IPI]
protein binding [IPI]
serine-type endopeptidase inhibitor activity [IDA, NAS]

Gene Ontology Cellular Component

Golgi apparatus [IDA]

endoplasmic reticulum [IDA]

extracellular region [NAS, TAS]

extracellular space [IDA, IMP]

extracellular vesicular exosome [IDA]

platelet alpha granule lumen [TAS]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

111283

9606

Interactors 172
Interactions 210
Chemical Interactions 4
Network
PTM Sites 1