Homo sapiens
PITX2
ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
paired-like homeodomain 2
GO Process (16)
GO Function (13)
GO Component (3)
Gene Ontology Biological Process
- camera-type eye development [IMP]
- cardiac neural crest cell migration involved in outflow tract morphogenesis [ISS]
- cell proliferation involved in outflow tract morphogenesis [ISS]
- deltoid tuberosity development [IMP]
- determination of left/right symmetry [ISS]
- hair cell differentiation [IC]
- iris morphogenesis [IMP]
- left/right axis specification [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- odontogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- prolactin secreting cell differentiation [TAS]
- regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription, DNA-templated [IDA]
- somatotropin secreting cell differentiation [TAS]
- spleen development [ISS]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- RNA polymerase II transcription factor binding [IPI]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- identical protein binding [IPI]
- phosphoprotein binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- ribonucleoprotein complex binding [IC]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription coactivator activity [IDA]
- RNA polymerase II transcription factor binding [IPI]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- identical protein binding [IPI]
- phosphoprotein binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- ribonucleoprotein complex binding [IC]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
111325
9606
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- Interactors 88
- Interactions 110
- Network