Homo sapiens
PROX1
prospero homeobox 1
GO Process (47)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
- aorta smooth muscle tissue morphogenesis [ISS]
- atrial cardiac muscle tissue morphogenesis [ISS]
- brain development [IEP]
- cerebellar granule cell differentiation [ISS]
- dentate gyrus development [ISS]
- dorsal spinal cord development [ISS]
- embryonic retina morphogenesis in camera-type eye [IEP]
- endocardium formation [ISS]
- hepatocyte differentiation [IEP]
- kidney development [IEP]
- lens development in camera-type eye [IEP]
- lens fiber cell morphogenesis [IEP]
- liver development [IEP]
- lung development [IEP]
- lymphangiogenesis [IDA]
- lymphatic endothelial cell differentiation [IDA]
- negative regulation of bile acid biosynthetic process [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- negative regulation of viral genome replication [IDA]
- neural tube development [ISS]
- neuronal stem cell maintenance [ISS]
- olfactory placode formation [ISS]
- optic placode formation involved in camera-type eye formation [ISS]
- otic placode formation [ISS]
- pancreas development [IEP]
- positive regulation of cell cycle [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- positive regulation of endothelial cell migration [IDA]
- positive regulation of endothelial cell proliferation [IDA]
- positive regulation of forebrain neuron differentiation [ISS]
- positive regulation of heart growth [ISS]
- positive regulation of neural precursor cell proliferation [ISS]
- positive regulation of sarcomere organization [ISS]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of circadian rhythm [IMP]
- regulation of gene expression [IDA]
- regulation of transcription involved in lymphatic endothelial cell fate commitment [IMP]
- retina morphogenesis in camera-type eye [ISS]
- skeletal muscle thin filament assembly [ISS]
- venous blood vessel morphogenesis [ISS]
- ventricular cardiac muscle tissue morphogenesis [ISS]
- ventricular cardiac myofibril assembly [ISS]
- ventricular septum morphogenesis [ISS]
Gene Ontology Molecular Function- DBD domain binding [IPI]
- DNA binding [IMP]
- LBD domain binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- core promoter sequence-specific DNA binding [ISS]
- ligand-dependent nuclear receptor binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IC]
- transcription corepressor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- DBD domain binding [IPI]
- DNA binding [IMP]
- LBD domain binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- core promoter sequence-specific DNA binding [ISS]
- ligand-dependent nuclear receptor binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IC]
- transcription corepressor activity [IDA]
- transcription regulatory region DNA binding [IDA]
Download Curated Data for this Protein
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- Interactors 38
- Interactions 41
- Network
- PTM Sites 14