Homo sapiens
SETMAR
HsMar1, METNASE, Mar1
SET domain and mariner transposase fusion gene
GO Process (15)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IDA, IMP]
- DNA double-strand break processing [IDA]
- DNA integration [IMP]
- cell proliferation [IMP]
- double-strand break repair via nonhomologous end joining [IDA, IMP]
- histone H3-K36 dimethylation [IMP]
- histone H3-K36 methylation [IDA, IMP]
- histone H3-K4 methylation [IDA]
- mitotic DNA integrity checkpoint [IMP]
- negative regulation of cell cycle arrest [IMP]
- negative regulation of chromosome organization [IDA]
- nucleic acid phosphodiester bond hydrolysis [IMP]
- positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [IDA, IMP]
- positive regulation of double-strand break repair via nonhomologous end joining [IDA]
- replication fork processing [IMP]
Gene Ontology Molecular Function- DNA topoisomerase binding [IPI]
- double-stranded DNA binding [IMP]
- endonuclease activity [IDA, IMP]
- histone methyltransferase activity (H3-K36 specific) [IDA]
- histone methyltransferase activity (H3-K4 specific) [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single-stranded DNA binding [IMP]
- single-stranded DNA endodeoxyribonuclease activity [IMP]
- structure-specific DNA binding [IDA, TAS]
- DNA topoisomerase binding [IPI]
- double-stranded DNA binding [IMP]
- endonuclease activity [IDA, IMP]
- histone methyltransferase activity (H3-K36 specific) [IDA]
- histone methyltransferase activity (H3-K4 specific) [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single-stranded DNA binding [IMP]
- single-stranded DNA endodeoxyribonuclease activity [IMP]
- structure-specific DNA binding [IDA, TAS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
112317
9606
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- Interactors 28
- Interactions 46
- Network
- PTM Sites 6