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Homo sapiens

SPAST

ADPSP, FSP2, SPG4

spastin

Alzheimer's Disease Project

GO Process (8)

GO Function (5)

GO Component (8)

Gene Ontology Biological Process

ATP catabolic process [IDA]

ER to Golgi vesicle-mediated transport [IMP]

cytokinesis, completion of separation [IMP]

cytoplasmic microtubule organization [IBA]

microtubule bundle formation [IDA]

microtubule severing [IDA]

protein hexamerization [IDA]

protein homooligomerization [IDA]

Gene Ontology Molecular Function

alpha-tubulin binding [IPI]
beta-tubulin binding [IPI]
microtubule binding [IDA]
microtubule-severing ATPase activity [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic vesicle [IDA]

endoplasmic reticulum [IDA]

extracellular vesicular exosome [IDA]

microtubule cytoskeleton [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

112562

9606

Interactors 64
Interactions 76
Network
PTM Sites 28