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Homo sapiens

TOP2B

TOPIIB, top2beta

topoisomerase (DNA) II beta 180kDa

GO Process (7)

GO Function (7)

GO Component (8)

Gene Ontology Biological Process

ATP catabolic process [IDA]

DNA topological change [IDA]

DNA unwinding involved in DNA replication [IBA]

mitotic DNA integrity checkpoint [IBA]

mitotic recombination [IBA]

resolution of meiotic recombination intermediates [IBA]

sister chromatid segregation [IBA]

Gene Ontology Molecular Function

DNA topoisomerase type II (ATP-hydrolyzing) activity [IDA]
chromatin binding [IDA]
enzyme binding [IPI]
histone deacetylase binding [IPI]
protein C-terminus binding [IPI]
protein heterodimerization activity [IPI]
protein kinase C binding [IPI]

Gene Ontology Cellular Component

DNA topoisomerase complex (ATP-hydrolyzing) [IBA]

cytoplasm [IDA]

heterochromatin [IDA]

nucleolus [IDA]

nucleoplasm [IDA]

CRISPR Database VEGA OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

113008

9606

Interactors 281
Interactions 335
Chemical Interactions 12
Network
PTM Sites 343