Homo sapiens
WRN
RECQ3, RECQL2, RECQL3
Werner syndrome, RecQ helicase-like
GO Process (21)
GO Function (17)
GO Component (4)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- DNA duplex unwinding [IDA, IMP]
- DNA metabolic process [IDA]
- DNA replication [IMP]
- DNA synthesis involved in DNA repair [IDA]
- aging [NAS]
- base-excision repair [IDA]
- cell aging [IMP]
- cellular response to DNA damage stimulus [IDA]
- cellular response to gamma radiation [IDA]
- cellular response to starvation [IDA]
- double-strand break repair [IMP]
- multicellular organismal aging [IMP]
- nucleic acid phosphodiester bond hydrolysis [IDA]
- nucleolus to nucleoplasm transport [IDA]
- positive regulation of hydrolase activity [IDA]
- regulation of apoptotic process [IGI]
- replication fork processing [IDA, IMP]
- response to UV-C [IDA]
- response to oxidative stress [IDA]
- telomere maintenance [IMP]
Gene Ontology Molecular Function- 3'-5' DNA helicase activity [IDA]
- 3'-5' exonuclease activity [IDA]
- ATP-dependent DNA helicase activity [IDA]
- ATPase activity [IDA]
- DNA binding [IDA]
- DNA helicase activity [IDA, IMP]
- G-quadruplex DNA binding [IDA]
- Y-form DNA binding [IDA]
- bubble DNA binding [IDA]
- exonuclease activity [IDA]
- four-way junction helicase activity [IDA]
- helicase activity [IDA]
- magnesium ion binding [IDA]
- manganese ion binding [IDA]
- protein binding [IPI]
- protein complex binding [IDA]
- protein homodimerization activity [IDA]
- 3'-5' DNA helicase activity [IDA]
- 3'-5' exonuclease activity [IDA]
- ATP-dependent DNA helicase activity [IDA]
- ATPase activity [IDA]
- DNA binding [IDA]
- DNA helicase activity [IDA, IMP]
- G-quadruplex DNA binding [IDA]
- Y-form DNA binding [IDA]
- bubble DNA binding [IDA]
- exonuclease activity [IDA]
- four-way junction helicase activity [IDA]
- helicase activity [IDA]
- magnesium ion binding [IDA]
- manganese ion binding [IDA]
- protein binding [IPI]
- protein complex binding [IDA]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 122
- Interactions 248
- Network
- PTM Sites 40