Homo sapiens
XDH
XO, XOR
xanthine dehydrogenase
GO Process (15)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- negative regulation of endothelial cell differentiation [IDA]
- negative regulation of endothelial cell proliferation [IDA]
- negative regulation of gene expression [IDA]
- negative regulation of protein kinase B signaling [IDA]
- negative regulation of protein phosphorylation [IDA]
- negative regulation of vascular endothelial growth factor signaling pathway [IDA]
- negative regulation of vasculogenesis [IDA]
- nucleobase-containing small molecule metabolic process [TAS]
- positive regulation of p38MAPK cascade [IDA]
- positive regulation of reactive oxygen species metabolic process [IDA]
- purine nucleobase metabolic process [TAS]
- purine nucleotide catabolic process [TAS]
- small molecule metabolic process [TAS]
- xanthine catabolic process [IDA]
Gene Ontology Molecular Function- 2 iron, 2 sulfur cluster binding [IDA]
- flavin adenine dinucleotide binding [IDA]
- molybdopterin cofactor binding [IDA]
- oxidoreductase activity, acting on the aldehyde or oxo group of donors [IBA]
- protein homodimerization activity [IPI]
- xanthine dehydrogenase activity [IDA]
- xanthine oxidase activity [EXP, IDA]
- 2 iron, 2 sulfur cluster binding [IDA]
- flavin adenine dinucleotide binding [IDA]
- molybdopterin cofactor binding [IDA]
- oxidoreductase activity, acting on the aldehyde or oxo group of donors [IBA]
- protein homodimerization activity [IPI]
- xanthine dehydrogenase activity [IDA]
- xanthine oxidase activity [EXP, IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
113335
9606
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- Interactors 35
- Interactions 29
- Chemical Interactions 26
- Network
- PTM Sites 1