Homo sapiens
HMGA2
BABL, HMGI-C, HMGIC, LIPO, STQTL9
high mobility group AT-hook 2
GO Process (42)
GO Function (19)
GO Component (6)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IDA]
- DNA damage response, detection of DNA damage [IDA]
- base-excision repair [IDA]
- chondrocyte differentiation [IDA]
- chondrocyte proliferation [IDA]
- chromatin organization [TAS]
- chromosome breakage [IDA]
- endodermal cell differentiation [IMP]
- epithelial to mesenchymal transition [IMP]
- fat cell differentiation [IMP]
- heterochromatin assembly [IDA]
- histone H2A-S139 phosphorylation [IDA]
- mesenchymal cell differentiation [IMP]
- mesodermal cell differentiation [IMP]
- mesodermal-endodermal cell signaling [IMP]
- mitotic G2 DNA damage checkpoint [IDA]
- multicellular organismal development [TAS]
- negative regulation by host of viral transcription [IDA]
- negative regulation of DNA binding [IDA]
- negative regulation of apoptotic process [IDA]
- negative regulation of double-strand break repair via nonhomologous end joining [IDA]
- negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- oncogene-induced cell senescence [IDA]
- positive regulation of apoptotic process [IDA]
- positive regulation of cell cycle arrest [IDA]
- positive regulation of cellular response to X-ray [IDA]
- positive regulation of cellular senescence [IMP]
- positive regulation of gene expression [IDA]
- positive regulation of response to DNA damage stimulus [IDA]
- positive regulation of stem cell proliferation [IDA, IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription regulatory region DNA binding [IDA]
- positive regulation of transcription, DNA-templated [IDA, IMP]
- regulation of cell cycle process [IDA]
- regulation of cellular response to drug [IDA]
- regulation of stem cell maintenance [IMP, TAS]
- regulation of transcription, DNA-templated [IMP]
- response to virus [IEP]
- senescence-associated heterochromatin focus assembly [IDA]
- stem cell differentiation [IEP]
Gene Ontology Molecular Function- 5'-deoxyribose-5-phosphate lyase activity [IDA]
- AT DNA binding [IDA, IMP]
- C2H2 zinc finger domain binding [IMP]
- DNA binding [NAS]
- DNA binding, bending [IDA, IMP]
- DNA-(apurinic or apyrimidinic site) lyase activity [IDA]
- DNA-dependent protein kinase activity [IDA]
- MH1 domain binding [IDA]
- MH2 domain binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SMAD binding [IPI]
- cAMP response element binding [IDA]
- core promoter binding [IDA]
- nucleosomal DNA binding [IDA]
- protein binding [IPI]
- regulatory region DNA binding [IDA]
- transcription factor binding [IPI]
- transcription factor binding transcription factor activity [IDA]
- 5'-deoxyribose-5-phosphate lyase activity [IDA]
- AT DNA binding [IDA, IMP]
- C2H2 zinc finger domain binding [IMP]
- DNA binding [NAS]
- DNA binding, bending [IDA, IMP]
- DNA-(apurinic or apyrimidinic site) lyase activity [IDA]
- DNA-dependent protein kinase activity [IDA]
- MH1 domain binding [IDA]
- MH2 domain binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SMAD binding [IPI]
- cAMP response element binding [IDA]
- core promoter binding [IDA]
- nucleosomal DNA binding [IDA]
- protein binding [IPI]
- regulatory region DNA binding [IDA]
- transcription factor binding [IPI]
- transcription factor binding transcription factor activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
113763
9606
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- Interactors 148
- Interactions 191
- Network
- PTM Sites 5