Homo sapiens
KLF4
EZF, GKLF, RP11-150J11.1
Kruppel-like factor 4 (gut)
GO Process (26)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- cellular response to growth factor stimulus [IDA]
- cellular response to laminar fluid shear stress [IMP]
- fat cell differentiation [ISS]
- mesodermal cell fate determination [TAS]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of cell migration involved in sprouting angiogenesis [IDA]
- negative regulation of cell proliferation [TAS]
- negative regulation of chemokine (C-X-C motif) ligand 2 production [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- negative regulation of heterotypic cell-cell adhesion [IDA]
- negative regulation of inflammatory response [TAS]
- negative regulation of interleukin-8 biosynthetic process [IDA]
- negative regulation of response to cytokine stimulus [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of cellular protein metabolic process [IMP]
- positive regulation of hemoglobin biosynthetic process [IMP]
- positive regulation of nitric oxide biosynthetic process [IMP]
- positive regulation of protein metabolic process [IGI]
- positive regulation of telomerase activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP, ISS]
- positive regulation of transcription, DNA-templated [ISS, NAS]
- post-embryonic hemopoiesis [IMP]
- regulation of cell differentiation [ISS]
- stem cell maintenance [ISS]
- transcription from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- RNA polymerase II transcription factor binding [IPI, ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- sequence-specific DNA binding transcription factor recruiting transcription factor activity [ISS]
- transcription regulatory region DNA binding [ISS]
- zinc ion binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- RNA polymerase II transcription factor binding [IPI, ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- core promoter proximal region sequence-specific DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- sequence-specific DNA binding transcription factor recruiting transcription factor activity [ISS]
- transcription regulatory region DNA binding [ISS]
- zinc ion binding [NAS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 158
- Interactions 222
- Network
- PTM Sites 3