Homo sapiens
HAND2
DHAND2, Hed, Thing2, bHLHa26, dHand
heart and neural crest derivatives expressed 2
GO Process (18)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- adult heart development [IEP]
- apoptotic process [ISS]
- cardiac neural crest cell development involved in outflow tract morphogenesis [ISS]
- heart development [NAS]
- heart looping [ISS]
- heart morphogenesis [ISS]
- in utero embryonic development [ISS]
- negative regulation of cardiac muscle cell apoptotic process [ISS]
- neural crest cell development [ISS]
- noradrenergic neuron differentiation [NAS]
- positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process [ISS]
- positive regulation of transcription regulatory region DNA binding [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- regulation of secondary heart field cardioblast proliferation [ISS]
- regulation of transcription, DNA-templated [ISS]
- thymus development [ISS]
Gene Ontology Molecular Function- AT DNA binding [IDA]
- E-box binding [IDA, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- activating transcription factor binding [ISS]
- protein binding [IPI]
- protein homodimerization activity [ISS]
- transcription coactivator activity [ISS]
- transcription factor binding [ISS]
- transcription regulatory region DNA binding [ISS]
- AT DNA binding [IDA]
- E-box binding [IDA, ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- activating transcription factor binding [ISS]
- protein binding [IPI]
- protein homodimerization activity [ISS]
- transcription coactivator activity [ISS]
- transcription factor binding [ISS]
- transcription regulatory region DNA binding [ISS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
114850
9606
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- Interactors 30
- Interactions 38
- Network
- PTM Sites 7