BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Homo sapiens

SAE1

AOS1, HSPC140, SUA1, UBLE1A

SUMO1 activating enzyme subunit 1

GO Process (7)

GO Function (7)

GO Component (5)

Gene Ontology Biological Process

SMT3-dependent protein catabolic process [IBA]

cellular protein metabolic process [TAS]

positive regulation of catalytic activity [TAS]

post-translational protein modification [TAS]

protein sumoylation [IDA, TAS]

protein ubiquitination [TAS]

regulation of mitotic cell cycle [IBA]

Gene Ontology Molecular Function

ATP-dependent protein binding [IDA]
SUMO activating enzyme activity [IDA]
enzyme activator activity [TAS]
protein C-terminus binding [IDA]
protein binding [IPI]
protein heterodimerization activity [IPI, TAS]
ubiquitin activating enzyme activity [TAS]

Gene Ontology Cellular Component

SUMO activating enzyme complex [IDA]

intracellular membrane-bounded organelle [IDA]

nucleoplasm [IDA, TAS]

nucleus [IDA, NAS]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Download Curated Data for this Protein

115366

9606

Interactors 146
Interactions 192
Network
PTM Sites 141