Homo sapiens
IRAK3
ASRT5, IRAKM
interleukin-1 receptor-associated kinase 3
GO Process (24)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- cytokine-mediated signaling pathway [ISS]
- interleukin-1-mediated signaling pathway [IMP]
- negative regulation of MAP kinase activity [IMP]
- negative regulation of NF-kappaB transcription factor activity [IMP]
- negative regulation of cytokine-mediated signaling pathway [IC]
- negative regulation of innate immune response [ISS]
- negative regulation of interleukin-12 production [IMP, ISS]
- negative regulation of interleukin-6 production [IMP, ISS]
- negative regulation of macrophage cytokine production [ISS]
- negative regulation of protein catabolic process [IMP]
- negative regulation of protein complex disassembly [IMP]
- negative regulation of toll-like receptor signaling pathway [ISS]
- negative regulation of tumor necrosis factor production [IMP]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of macrophage tolerance induction [ISS]
- protein phosphorylation [IDA]
- regulation of protein complex disassembly [ISS]
- response to exogenous dsRNA [ISS]
- response to interleukin-1 [IMP]
- response to lipopolysaccharide [ISS]
- response to peptidoglycan [ISS]
- response to virus [IC]
- toll-like receptor signaling pathway [IBA]
Gene Ontology Molecular Function
Download Curated Data for this Protein
116382
9606
Switch View:
- Interactors 35
- Interactions 35
- Chemical Interactions 3
- Network
- PTM Sites 5