Homo sapiens

CARD8

CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN

caspase recruitment domain family, member 8

GO Process (4)

GO Function (4)

GO Component (4)

Gene Ontology Biological Process

activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]

negative regulation of I-kappaB kinase/NF-kappaB signaling [IDA]

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]

positive regulation of interleukin-1 beta secretion [IDA]

Gene Ontology Molecular Function

NACHT domain binding [IPI]
cysteine-type endopeptidase activator activity involved in apoptotic process [IDA]
protein binding [IPI]
protein homodimerization activity [IDA]

Gene Ontology Cellular Component

NLRP3 inflammasome complex [IDA]

cytoplasm [IDA]

nucleoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Download Curated Data for this Protein

116564

9606

Interactors 53
Interactions 112
Network
PTM Sites 11