Homo sapiens
PHF8
JHDM1F, MRXSSD, ZNF422, RP13-444K19.2
PHD finger protein 8
GO Process (10)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- brain development [ISS]
- histone H3-K27 demethylation [IDA]
- histone H3-K36 demethylation [IDA]
- histone H3-K9 demethylation [IDA]
- histone H4-K20 demethylation [IDA]
- mitotic cell cycle [TAS]
- negative regulation of chromatin silencing at rDNA [IDA]
- positive regulation of transcription from RNA polymerase I promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA, IMP]
Gene Ontology Molecular Function- chromatin binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K27 specific) [IDA]
- histone demethylase activity (H3-K36 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H4-K20 specific) [IDA]
- iron ion binding [IDA]
- methylated histone binding [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
- protein binding [IPI]
- zinc ion binding [IDA]
- chromatin binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K27 specific) [IDA]
- histone demethylase activity (H3-K36 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H4-K20 specific) [IDA]
- iron ion binding [IDA]
- methylated histone binding [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
- protein binding [IPI]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
116751
9606
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- Interactors 187
- Interactions 232
- Network
- PTM Sites 96