Homo sapiens
GREM1
C15DUPq, CKTSF1B1, CRAC1, CRCS4, DAND2, DRM, DUP15q, GREMLIN, HMPS, HMPS1, IHG-2, MPSH, PIG2
gremlin 1, DAN family BMP antagonist
GO Process (27)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- activation of transmembrane receptor protein tyrosine kinase activity [ISS]
- cell migration involved in sprouting angiogenesis [ISS]
- cell morphogenesis [IDA]
- collagen fibril organization [IMP]
- determination of dorsal identity [IMP]
- negative regulation of BMP signaling pathway [IDA, IMP]
- negative regulation of bone mineralization [IMP]
- negative regulation of bone mineralization involved in bone maturation [IMP]
- negative regulation of bone remodeling [IMP]
- negative regulation of bone trabecula formation [IMP]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of monocyte chemotaxis [ISS]
- negative regulation of osteoblast proliferation [IMP]
- negative regulation of osteoclast proliferation [IMP]
- negative regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- positive regulation of cardiac muscle cell differentiation [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of peptidyl-tyrosine autophosphorylation [ISS]
- positive regulation of receptor activity [ISS]
- positive regulation of receptor internalization [ISS]
- positive regulation of telomerase activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [ISS]
- regulation of epithelial to mesenchymal transition [IMP]
- regulation of stress-activated MAPK cascade [ISS]
- signal transduction [ISS]
- signal transduction by p53 class mediator [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
117754
9606
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- Interactors 5
- Interactions 5
- Network
- PTM Sites 2